Welcome to École polytechnique learning platform

The Ecole polytechnique learning platform, based on Moodle, allows you to find the individual courses (lectures, seminars, projects, etc.) which make up our academic programs.

This platform is synchronised with our course catalog SynapseS available at https://synapses.polytechnique.fr/.

You can search by name or code (see browser below) or click on the current academic year (menu on the left) in order to browse by Subject Area.

Please note that not all courses are available to all students. If you are unsure whether or not you can register for a particular course, you should contact the professors in charge of your program. For the “Diplôme d’ingénieur” and Master Université Paris Saclay, you will find the detailed curriculum on this website: https://portail.polytechnique.edu/etudes/fr.  For the Graduate Degree programs, please use this website: https://portail.polytechnique.edu/graduatedegree/

While care has been taken to ensure the accuracy of this learning platform, courses may be subject to change subsequently. Please contact professors in charge of the courses for further information.


    Cours disponibles

    Biology (BIO 101) is a molecular and cellular biology course, which provides all the concepts required for a scientific understanding of living systems. This course aims both at preparing students for the biology option, which is available in the Mathematics & Computer Science and Mathematics & Physics majors, and at raising awareness about socio-economic issues related to biology, such as health, ethics or bioengineering.

    Prerequisite: BIO101

    Cell Biology (BIO201) introduces

    students to the mechanisms that cells

    use to regulate the physical properties of

    their dynamic architecture, to produce

    force and move, to compartmentalize and

    transport proteins, to regulate growth

    and death, and to communicate with

    their environment. The course focuses on

    human cells, and emphasis is placed on

    human diseases where appropriate. Upon

    course completion, students have a comprehensive

    understanding of the function

    and architecture of cells.

    Because experimentation is at the heart

    of progress in cell biology, 50% of classes

    contain practical work, completed over

    the course of the semester. The intention

    is to allow students to develop their

    knowledge in the subject area, to acquire

    sound scientific reasoning, and to become

    familiar with the main techniques of

    modern cell biology, like quantitative

    microscopy imaging and computerassisted

    data analysis.




     Cell Biology (BIO 201) introduces students to the mechanisms that cells use to regulate the physical properties of their dynamic architecture, to produce force and move, to compartmentalize and transport proteins, to regulate growth and death, and to communicate with their environment. The course focuses on human cells, and emphasis is placed on human diseases where appropriate. Upon course completion, students have a comprehensive understanding of the function and architecture of cells.

    Because experimentation is at the heart of progress in cell biology, 50% of classes contain practical work, completed over the course of the semester. The intention is to allow students to develop their knowledge in the subject area, to acquire sound scientific reasoning, and to become familiar with the main techniques of modern cell biology, like quantitative microscopy imaging and computer-assisted data analysis.

    Molecular Genetics (BIO 202) provides an in-depth understanding of the mechanisms by which living organisms store, express and transmit genetic information and the basis of human genetic diseases. Lectures will cover a range of topics, including the molecular aspects of DNA replication and transcription, translation of RNA into protein and gene regulations. This course will also cover the latest methodologies used in genomics analysis, like DNA sequencing. Because experimentation is at the heart of progress in cell biology, 50% of classes contain practical work, completed over the course of the semester. The intention is to allow students to develop their knowledge in the subject area, to acquire sound scientific reasoning, and to combine the modern techniques in molecular genetics with computer-assisted data analysis.

    Prerequisite: BIO202
    The primary goal of the Biology practicals
    is to provide an overview of the most
    recent techniques used by researchers in
    biology to complement the practicals of
    BIO201 and BIO202. During this course,
    students will rotate in several research
    laboratories of École Polytechnique where
    they will learn some of the most advanced
    techniques in microscopy and genetic
    manipulations under the supervision of
    researchers.




    The primary goal of the biology practicals is to provide an overview of the most recent techniques used by researchers in biology to complement the practicals of BIO201 and BIO202. During this course, students will rotate in several research laboratories of Ecole Polytechnique where they will learn some of the most advanced techniques in microscopy and genetic manipulations under the supervision of researchers.

    The cancer biology course will include a series of lectures covering the molecular and cellular mechanisms of cancer development and current anti-cancer strategies. In parallel, students will actively participate in a new ambitious research and teaching program developed at Ecole Polytechnique thanks to the sponsoring of the pharmaceutical company Servier and the biotechology company Cellectis. This experimental project aims at reconstituting the tumoral process of cancer development using only the mutation repertoire found in a single breast cancer patient.

    Les théories de la biodiversité sont à l'interface entre l'écologie et l'évolution. Les processus qui interviennent dans la genèse et le maintien de la biodiversité sont présentés. Ces processus sont de nature génétique (sélection naturelle, mutation, dérive, systèmes de reproduction), macroévolutive (spéciation, extinction), et écologique (maintien du polymorphisme, structuration biogéographique, niche écologiques). Ces concepts sont abordés sous forme de modèles qui font intervenir la théorie des jeux, les modèles spatialement structurés, la génétique des populations et la dynamique des populations, mais aussi à l'aide d'étude de cas particuliers.
    Ce cours traite aussi de l'application de ces théorie à la gestion de la biodiversité, au niveau populationnel (diminution de la variabilité génétique, réponse à la sélection et potentialités adaptatives) et des communautés écologiques (réponse de communautés à des changements climatiques ou autres, rôle d'assurance de la biodiversité).

    Langue du cours : Français
    Credits ECTS : 5




    Ecology and Biodiversity

    The theories of the biodiversity lie at the interface between ecology and evolution. The processes underlying the origin and the maintenance of
    biodiversity are presented. These processes are genetic (natural selection, mutation, genetic drift, systems of reproduction), macro-evolutionary
    (speciation, extinction), and ecological (maintenance of polymorphism, biogeography, ecological niches). These concepts are approached in the form
    of models using game theory, spatially structured models, population genetics and population dynamics, but also with the study of particular cases.
    This course also presents applications of these theories to the management of the biodiversity, at the population level (reduction in genetic variability,
    response to selection and adaptive potentialities

    Level : UnderGraduate
    Course Language : French

    Ce cours de 2ème année illustre quelques pathologies et les méthodes les plus actuelles pour les prendre en charge. Les pathologies choisies sont celles qui représentent les plus grands défis pour nos sociétés développées. Ce cours de biomédecine insiste sur le substrat biologique des pathologies et des traitements et fait une place à l’économie de la santé.

     

    Les 10 blocs sont :

    • Maladies génétiques et thérapie génique
    • Modèles animaux
    • Le médicament
    • Neuropsychiatrie
    • Maladies neurodégénératives
    • Le diabète
    • Origine des cancers
    • Thérapies des cancers
    • Vieillissement et cancer
    • Révisions

     

    Il est préférable d’avoir assimilé les notions introduites dans les cours de Biologie moléculaire et information génétique (BIO452) et Biologie cellulaire et développement BIO451) qui précèdent. Cependant ce ne sont pas des prérequis, car les notions fondamentales seront rappelées et le cours a pour ambition de pouvoir être suivi par tout élève que la biologie et la médecine intéressent. Mais il faut savoir que c’est un cours exigeant beaucoup d’investissement personnel pour les élèves n’ayant pas fait de biologie au préalable.

    Langue du cours : Français
    Credits ECTS : 5

    Course Language : French

     

     

     




    Pathologies and therapeutic strategies

    This 2nd year course illustrates some pathologies and the most current methods to take care of them. The pathologies chosen are those that represent the greatest challenges for our developed societies. This biomedical course portrays the biological substrate of pathologies and treatments as well as the economy of health.

    The 10 blocks are:

    • Genetic diseases
    • Animal models
    • Medication
    • Infectious diseases
    • Neuropsychiatry
    • Neurodegenerative diseases
    • Diabetes
    • Cancer biology
    • Treatment of cancers
    • Aging

    The courses of Molecular Biology and genetic information and Cell Biology and Development that precede helps to understand this course, but are not compulsory prerequisites. However, fundamental notions will be recalled and the course might be followed by any interest student at the price of personal investment.

    Level : Graduate
    Course Language : French

     

     

     

    La cellule est l’unité structurale et fonctionnelle de tous les organismes vivants. Le but de ce cours est de décrire l’organisation et le fonctionnement de la cellule, ainsi que la façon dont un organisme complexe se construit à partir de ces briques élémentaires. Ce cours permet la découverte de la biologie cellulaire et de la biologie du développement, disciplines centrales des sciences de la vie, à l’interface avec de nombreux autres aspects de la biologie, mais aussi avec la physique, la chimie, l’informatique et les sciences de l’ingénieur.

    Les principales thématiques abordées seront :

    • l’organisation interne de la cellule (membranes, compartimentation, trafic)
    • l’intégration de la cellule dans son environnement
    • la multiplication et la mort cellulaire
    • la construction d’un organisme multicellulaire complexe (apparition de types cellulaires différents, cellules souches, mise en place d’axes de symétrie et régionalisation, morphogenèse).

    BIO451 constitue une base solide et conseillée pour les autres cours de biologie d’année 2 et 3. Il est complémentaire de BIO452, et il est de ce fait recommandé d’avoir suivi BIO452.

    Langue du cours : Français
    Credits ECTS : 5

     

     

     



    Cell Biology and Development

    The cell is the basic structural, functional and biological unit of all known living organisms. This course will reveal the organization, functions and
    dysfunctions of the cell. Bio451 provides a broad introduction to cell biology, a discipline central to life sciences, at the interface with many other
    aspects of biology but also with physics, chemistry, computer and engineering sciences.
    After a quick description of the molecular components essential to living cells and of the key steps leading to the emergence of life on earth, students
    will discover the dynamic organization of the cell. How cells can assemble to form complex multicellular organisms will also be discussed. Finally,
    emphasis will be placed on the regulation of cellular functions (multiplication, dead cell, cell migration) by their microenvironment. This course will end
    on notions of Virology and Oncology, pathologies associated with disruption of cellular functions, and thus confront students with the crucial health
    problem.

    Requirements :BIO451 provides strong and recommended knowledge for other second and third year biology courses. It is complementary to BIO452, and having followed BIO452 is recommended.

    Langue du cours : French
    Credits ECTS : 5

    Cet enseignement permet la découverte d’une discipline de base et constitue un passeport conseillé pour les autres cours de biologie de l’année 2 et les programmes d'approfondissement de l’année 3 proposés par le département.

    Il dégagera la logique de fonctionnement du monde vivant et montrera comment la biologie, discipline actuellement en plein essor, se développe de plus en plus à l’interface avec la physique, la chimie, l’informatique et les sciences de l’ingénieur.

    Ce cours présentera d’abord les propriétés caractéristiques et les molécules informatives (ADN, ARN et protéines) partagées par les êtres vivants. Les principales régulations asservissant la production des ARN et des protéines seront ensuite détaillées. Ceci permettra de comprendre comment les cellules régulent l'expression de leurs gènes pour répondre à leurs besoins et s’adapter à des changements de leur environnement.

    Langue du cours : Français
    Credits ECTS : 5




    BIO452 Molecular Biology and genetic information
    Teaching coordinator : Arnaud ECHARD

    This course provides a broad introduction to an essential field and prepares for several other 2nd year biology courses, as well as for more advanced, 3rd year programs.
    This course will reveal the logic of life and will show how biology, an expanding scientific discipline, is developing more and more at the interface with physics, chemistry, informatics, mathematics and engineer sciences.
    The structure and function of the main biological macromolecules (DNA, RNA and proteins) are presented, along with the regulation systems that control their production and adapt it to cellular needs.

    Level : Graduate
    Course Language : French