Quantitative study of size homoeostasis in the fission yeast S. pombe
Interdisciplinarity is key in today's life sciences. On top of the experimental techniques of biology and biochemistry, applied mathematics, computer science or physics are increasingly mandatory for the quantitative study of a biological question. In particular, imaging through fluorescence microscopy and the automated analysis of the resulting acquired images play a crucial role in the study of dynamical phenomenon in vivo. Following that spirit, we will look at cell growth and size homoeostasis in the fission yeast S. pombe, using classical experimental biology techniques to build genetically modified strains, video-microscopy to observe them in vivo and image analysis to obtain quantitative data, which will be confronted to simple models and simulations.
Note: This module contains a practical experimental biology part as well as a computational part in Python.
Course language: French
ECTS credits: 4
- Teaching coordinator: Chessel Anatole
- Teaching coordinator: Mechulam Yves