La bioinformatique se développe aujourd'hui rapidement et dans plusieurs directions, qui vont de la molécule à la cellule : analyses et comparaisons de génomes, modélisation de molécules biologiques et de leurs interactions, modélisation de processus cellulaires.

Les principaux aspects abordés dans ce cours seront :

  • Comparaisons et alignements de séquences
  • Séquençage d'ADN et reconstruction de génomes
  • Modèles statistiques de séquences d'ADN
  • Prédictions de structure des ARN et des protéines
  • Phylogenie
  • Réseaux cellulaires d'interaction et de régulation

Les petites classes inclueront des aspects algorithmiques, quelques exercices pratiques sur ordinateur, et des systèmes d'importance biologique tels que le ribosome ou le virus SARS.


Niveau requis :
Au moins un module de biologie en année 2 (ou bien prévoir de fournir un travail personnel plus important)
Language of the course:
Anglais
Credits ECTS : 4

 

Computational biology

Today, bioinformatics is developing rapidly and in several directions, ranging from molecule to cell: analysis and comparisons of genomes, modeling of biological molecules and their interactions, and modeling of cellular processes.

The main aspects covered in this course will be:

Comparison and alignment of sequences
DNA sequencing and genome reconstruction
Statistical models of DNA sequences
RNA and protein structure predictions
Phylogeny
Cellular interaction and regulation networks

The small classes will include algorithmic aspects, some practical exercises on computer, and systems
Biological significance such as ribosome or SARS.

Required level: At least one biology module in year 2 (or plan to provide more personal work).
Language of the course: English
Credits ECTS : 4




Computational biology


Today, bioinformatics is developing rapidly and in several directions, ranging from molecule to cell: analysis and comparisons of genomes, modeling of biological molecules and their interactions, and modeling of cellular processes.

The main aspects covered in this course will be:

Comparison and alignment of sequences
DNA sequencing and genome reconstruction
Statistical models of DNA sequences
RNA and protein structure predictions
Phylogeny
Cellular interaction and regulation networks

The small classes will include algorithmic aspects, some practical exercises on computer, and systems
Biological significance such as ribosome or SARS.

Required level: At least one biology module in year 2 (or plan to provide more personal work).